Osaka, Japan, August 7, 2025 – Ono Pharmaceutical, Co., Ltd. (Headquarters: Osaka, Japan; President: Toichi Takino; “Ono”) today announced that it was continuously selected as a constituent stock of the following ESG (Environmental, Social and Governance) investment indexes adopted by the Government Pension Investment Fund (GPIF), and ESG investment indexes provided by FTSE Russell.

＜ESG investment indexes adopted by GPIF＞

• MSCI Nihonkabu ESG Select Leaders Index (2 consecutive years from 2024)

  Among the stocks that make up the MSCI Japan Equity IMI Index, this index is composed of Japanese companies with excellent ESG evaluations from each industry.

• FTSE Blossom Japan Index (8 consecutive years from 2018)

  Among the stocks that make up FTSE Japan All Cap Index, this index is composed of Japanese companies with excellent ESG evaluations.

• FTSE Blossom Japan Sector Relative Index (4 consecutive years from 2022)

  This Index is based on the same ESG evaluations as the FTSE Blossom Japan Index, with additional evaluations of the scale of its environmental burden and management of climate change risks.

• S&P/JPX Carbon Efficient Index (8 consecutive years from 2018)

  This index targets stocks that make up the Tokyo Stock Price Index (TOPIX), and is composed of Japanese companies with excellent evaluations in environmental information disclosure and carbon efficiency (carbon emissions per unit of revenue).

• Morningstar Japan ex-REIT Gender Diversity Tilt Index (Operated from 2023, selected)

  This index is composed of companies selected for their excellent evaluations in gender diversity efforts, based on research by Equileap.

＜FTSE Russell＞

• This international index is composed of companies that are selected for their relatively excellent ESG practices in each industry.

 Based on the corporate philosophy of “Dedicated to the Fight against Disease and Pain,” Ono continues to contribute to the sustainable development of society through the ESG perspective business activities and has been committed to enhancing sustainable corporate value.（ https://sustainability.ono-pharma.com/en ）