Licensing & Co-promotion

Main Achievements

FY

Partners

Title

2023

NEX-I

Ono Enters into a License Agreement with NEX-I to Develop and Commercialize NXI-101

AstraZeneca

Settlement Agreement over lawsuits on PD-L1 and CTLA-4 antibody patents with AstraZeneca

2022

Equillium

Ono and Equillium Announce Exclusive Option and Asset Purchase Agreement for the Development and Commercialization of Itolizumab

2020

Ribon Therapeutics

ONO enters into License Agreement with Ribon Therapeutics for the Development and Commercialization of RBN-2397, a PARP7 Inhibitor, in Japan, South Korea, Taiwan and ASEAN Countries

Chordia Therapeutics

ONO Enters into Exclusive License Agreement with Chordia Therapeutics on CTX-177, a MALT1 Inhibitor, and its Related Compounds(131 KB)

Roche

ONO and Bristol Myers Squibb Enter Patent License Agreement with Roche

SK Biopharmaceuticals

Ono Enters into License Agreement on Cenobamate, an Antiepileptic Drug with SK Biopharmaceuticals

2019

Nichi-Iko

ONO and Nichi-Iko Enter into Licensing Agreement and Technical Collaboration for Limaprost Alfadex Tablets

Forty Seven

ONO and Forty Seven, Inc. Sign a License Agreement to Develop, Manufacture and Commercialize 5F9 in Japan, South Korea, Taiwan and Other Selected Countries in Southeast Asia

Rafael Pharmaceuticals

ONO Enters into Exclusive License Agreement with Rafael Pharmaceuticals on CPI-613 (devimistat), a Cancer Metabolism Inhibitor, and Other Related Compounds

2017

Bristol-Myers Squibb

ONO Enters into License Agreement with Bristol-Myers Squibb for Prostaglandin E2 Receptor Antagonists relating to Immuno-Oncology Programs

Karyopharm

Ono Enters into Exclusive License Agreement with Karyopharm to Develop and Commercialize Selinexor and KPT-8602, XPO1 Inhibitors

Seikagaku

Ono and Seikagaku Reach a Definitive Agreement Related to Co-development and Marketing Collaboration on SI-613 for the Treatment of Osteoarthritis in Japan

Array Biopharma

ONO Concludes a License Agreement with Array Biopharma related to Binimetinib, a MEK inhibitor and Encorafenib, a BRAF inhibitor

2016

Merck

Ono Pharmaceutical Company and Bristol-Myers Squibb Enter Settlement and License Agreement with Merck for Anti-PD-1 Antibody Patent Infringement Litigation

Celyad

ONO enters into license agreement with Celyad for its allogeneic CAR T-cell therapy (NKR-2)

IDAC

ONO Enters an Agreement with IDAC Theranostics relating to Exclusive Evaluation and License Negotiation on IT1208, anti-CD4 antibody

2015

Santen

ONO Enters Licensing Agreement with Santen for ONO-9054, FP/EP3 Dual Receptor Agonist

2014

China Chemical & Pharmaceutical

ONO and CCPC enter into an agreement on development and commercialization of Limaprost in Taiwan

GILEAD

ONO AND GILEAD ANNOUNCE EXCLUSIVE LICENSE AGREEMENT TO DEVELOP BTK INHIBITOR, ONO-4059, FOR THE TREATMENT OF B-CELL MALIGNANCIES AND OTHER DISEASES

Meiji Seika Pharma

Ono and Meiji Seika Pharma enter into an agreement on development and commercialization of Limaprost in Thailand and Indonesia

Bristol-Myers Squibb

ONO PHARMACEUTICAL CO., LTD. and Bristol-Myers Squibb Announce Strategic Immuno-Oncology Collaboration in Japan, South Korea and Taiwan

2013

AstraZeneca

AstraZeneca and Ono Enter Co-promotion Agreement in Japan for Dapagliflozin

Valeant

Ono Enters into License Agreement with Valeant

Dainippon Sumitomo

Ono and Dainippon Sumitomo reach agreement on expanding business relating to Limaprost into China

Bial

Ono Enters into License Agreement with Bial

2011

Merck KGaA

Ono to Enter into License Agreements with Merck KGaA

Bristol-Myers Squibb

Ono and Bristol-Myers Squibb Enter into Strategic Agreement for Anti-PD-1 Antibody,ONO-4538/BMS-936558,and ORENCIA®(abatacept),Rheumatoid Arthritis Agent

KAI Phamaceuticals

Ono Enters into License Agreement with KAI Phamaceuticals,Inc.for KAI 4169

Servier

Ono Enters into License Agreement with Servier for Ivabradine

2010

OncoTherapy

Ono Enters into License Agreement with OncoTherapy for New Therapeutic Cancer Peptide Vaccines

Concordia

Ono Enters into License Agreement with Concordia for New Therapeutic Agent for Pancreatic Cancer

Onyx

Ono Announces Carfilzomib Development and Commercialization Agreement with Onyx Pharmaceuticals for Japan

2009

Tioga

License Agreement of a Drug Candidate for Irritable Bowel Syndrome with Tioga

2008

Progenics

Ono Enters into License Agreement with Progenics

2007

Nissan Chemical

Ono Enters into License Agreement with Nissan Chemical for New Therapeutic Agent for Thrombocytopenia

CeNeS

Ono Enters into License Agreement with CeNeS Limited - New Intravenous Anaesthetic -

2006

Sapphire

Ono Enters into License Agreement with Sapphire Therapeutics, Inc. in Japan,Korea and Taiwan - New Drug for the Treatment of Cancer Anorexia/Cachexia -

2005

Santen

Licensing Agreement on PDE4 Inhibitor ONO-6126

Novartis

Agreement on Joint Development and Marketing of Rivastigmine Transdermal Patch for the Treatment of Alzheimer's Disease

Merck

Results of Phase II Studies of Sitagliptin (MK-0431 / ONO-5345) Investigational Treatment for Type 2 Diabetes Presented by Merck & Co., Inc. at ADA